Do you suffer from asthma that causes disruptions in your sleep?
This clinical research study is looking at the safety and effectiveness of an medication for people with persistent asthma, and the way their condition affects their sleep.
Would you like to take part?
As a volunteer in a research study, you’ll receive study-related medical care from the study doctor and regular follow up of your asthma to monitor the effectiveness of the care you’ll receive. The results of this research will be used to find out if the investigational medication being studied will be of benefit to others with asthma, and whether it will be made widely available to all patients with asthma. Study volunteers are an important part of moving medical care forward.
You may qualify to participate in this study if you:
- Have a physicians diagnosis of asthma for greater than or equal to 12 months, treated with medium to high dose inhaled corticosteroid (ICS) and a second controller
- Have had at least one asthma exacerbation within 1 year prior to screening. Exacerbation is defined as deterioration of asthma that results in emergency treatment, hospitalization due to asthma, or treatment with systemic steroids
- Greater or equal to 1 awakening during the night due to asthma symptoms in the week before screening
You may not qualify to participate if you:
- Experience an asthma exacerbation during screening, prior to randomization
- Are a current smoker, or a former smoker with >10 year pack history. If you wish to calculate your pack-years, please use this website: https://www.smokingpackyears.com/
- Have a history or clinical evidence of COPD
- Have history or current evidence of clinically significant non-respiratory diseases that may interfere with the aims of the study or put you at risk
- Experience sleep disturbances not related to asthma, including sleep apnea, hypersomnia, or insomnia secondary to chronic pain, atopic dermatitis (AD), COPD or other conditions
- Are currently being treatment with antidepressants, lipophilic beta blockers, clonidine, opioids, or other medications known to interfere with sleep and may confound the study assessments, as determined by the Investigator
There are other eligibility requirements that the study doctor will review. Only the study doctor can finally determine whether you are eligible to participate in the study or not.