A cat allergy can contribute to constant allergy symptoms, as exposure can occur at work, school, day care or in other indoor environments, even if a pet is not present. Cat allergy symptoms include sneezing, runny nose, coughing, watery or itchy eyes, and skin rashes.
Are you a cat owner who is allergic to cats?
This clinical research study is looking at the safety and effectiveness of an investigational medication option for people who suffer from cat allergies and live with a cat.
Would you like to take part?
As a volunteer in a research study, you’ll receive study-related medical care from the study doctor and regular follow up of your condition to monitor the safety and effectiveness of the care you’ll receive. Study volunteers are an important part of moving medical care forward.
You may qualify to participate in this study if you:
- Are a generally healthy male or female, 12 years of age or older
- Weigh greater than or equal to 40kg at time of screening
- Have documented or patient reported history (for at least 2 years) of symptomatic cat allergen-triggered allergic rhinitis with or without conjunctivitis and with or without asthma as defined by all of the following criteria:
- Positive skin prick test (SPT) with cat hair extract (mean wheal diameter at least 5 mm greater than a negative control) at screening
- Positive allergen-specific IgE (sIgE) tests for cat hair and Fel d 1 (≥0.7 kUa/L at screening)
- Documented or patient reported history of nasal and/or ocular symptoms upon cat exposure
- Symptomatic despite the use of medications to treat their nasal and/or ocular symptoms
- At least 1 generally healthy cat (that is unlikely to die during the study) living in the home resulting in regular exposure
You may not qualify to participate in this study if you:
- History of significant multiple and/or severe allergies that would potentially interfere with the assessments during the baseline and 12-week efficacy assessment periods or confound results, per investigator discretion, including significant rhinitis or sinusitis due to daily contact with other allergens causing symptoms that are expected to coincide with the baseline period or any of the efficacy assessment periods
- Active lung disease other than asthma
- Treatment with an investigational drug within 2 months or within 5 half-lives (if known), whichever is longer, prior to screening
- Persistent chronic or recurring acute infection requiring treatment with antibiotics, antivirals, or antifungals, or any untreated respiratory infections within 4 weeks prior to screening. Patients may be re-evaluated after resolution of symptoms and specified time duration