Diabetes is a condition in which your blood glucose, or blood sugar, levels are too high. With type 2 diabetes, the more common type, your body does not make or use insulin well. Insulin is a hormone that helps glucose get into your cells to give them energy. Without insulin, too much glucose stays in your blood. Over time, high blood glucose can lead to serious problems with your heart, eyes, kidneys, nerves, and gums/teeth.
Have you been diagnosed with type 2 diabetes within the last 4 years?
This clinical research study is looking at the safety and effectiveness of an investigational medication option for volunteers with early type 2 diabetes.
Would you like to take part in type 2 diabetes research?
As a volunteer in a research study, you’ll receive study-related medical care from the study doctor and regular follow up of your diabetes to monitor the safety and effectiveness of the care you’ll receive. Study volunteers are an important part of moving medical care forward.
You may qualify to participate in this study if you:
- Have, within the last 4 years, been diagnosed with Type 2 Diabetes based on the World Health Organization classification or other locally applicable diagnostic standards
- Have HbA1c ≥7% to ≤9.5% as determined by a central laboratory
- Have been on a stable treatment of metformin only at least 90 days preceding your baseline visit
- with the minimum effective dose of ≥1500 mg/day, but not higher than the maximum approved dose per country-specific label, or
- <1500 mg/day in case of intolerance of full therapeutic dose
You may not qualify to participate in this study if you:
- Have Type 1 Diabetes mellitus
- Have a history of chronic or acute pancreatitis any time prior to study entry
- Have a history of:
- proliferative diabetic retinopathy
- diabetic macular edema
- no proliferative diabetic retinopathy requiring immediate or urgent treatment
- Are at risk for cardiovascular disease in the investigators opinion or have a history of any of these CV conditions prior to study entry:
- myocardial infarction
- percutaneous coronary revascularization procedure
- carotid stenting or surgical revascularization
- nontraumatic amputation
- peripheral vascular procedure
- cerebrovascular accident, or congestive heart failure
- Have family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2
There are other eligibility requirements that the study doctor will review. Only the study doctor can determine whether you are eligible to participate in the study or not.
Fill out our diabetes questionnaire for priority access to all our diabetes studies: https://joinastudy.ca/questionnaire/diabetes/