Do you have type 2 diabetes, or are you currently struggling with weight related issues?
This clinical research study is broken into 2 sections, the first looking at the safety and effectiveness of a medication for type 2 diabetics, and the second evaluating an experimental weight loss treatment for overweight and obese adults.
Would you like to take part?
As a volunteer in a research study, you’ll receive study-related medical care from the study doctor and regular follow-up of your health to monitor the effectiveness of the care you’ll receive. The results of this research will be used to find out if the investigational medication being studied will be of benefit to others struggling with these conditions, and whether it will be made widely available to all Canadians trying to manage them. Study volunteers are an important part of moving medical care forward.
You may qualify to participate in this study if you:
- Are between the ages of 18 and 75, inclusive
- For the type 2 diabetes section:
- Have been diagnosed with inadequately controlled type 2 diabetes while being on metformin
- Have a BMI greater than or equal to 23.0 kg/m2
- For the obesity section:
- Have a BMI greater than or equal to ≥30.0 kg/m2
You may not qualify to participate if you:
- Suffer from any of the following:
- Active/current, symptomatic gallbladder disease
- Have a history of pancreatitis in the prior 2-months
- Have a history of Type 1 Diabetes Mellitus, or secondary forms of diabetes
- Have any condition affecting drug absorption
- Have a medical history of active liver disease
- Any use of pharmacological agents with approved indication for weight loss
- For the type 2 diabetes section:
- Use of any agent (other than metformin) for the explicit purpose of glycemic control
- History of diabetic ketoacidosis
- Proliferative retinopathy or maculopathy requiring acute treatment
- For the obesity section:
- Previous or planned weight reduction surgery
- Major depressive disorder or other severe psychiatric disorders
- Any lifetime history of a suicide attempt
- Have any clinically significant cardiovascular conditions
- Have uncontrolled blood pressure
- Any other medical or psychiatric condition that may increase the risk of study participation or, in the investigator’s judgment, make the participant inappropriate for the study
There are other eligibility requirements that the study doctor will review. Only the study doctor can finally determine whether you are eligible to participate in the study or not.