Obesity and Chronic Kidney Disease Research Study

Are You Struggling With Obesity, or Being Overweight and Also Suffer from Chronic Kidney Disease?

The main purpose of this study is to investigate the effect of retatrutide on renal function in participants with obesity and chronic kidney disease (CKD), with or without Type 2 Diabetes (T2D). The study will last around 31 weeks.

Would you like to take part?

As a volunteer in a research study, you’ll receive study-related medical care from the study doctor and regular follow-up of your health to monitor the effectiveness of the care you’ll receive. The results of this research will be used to find out if the investigational medication being studied will be of benefit to others struggling with obesity, and whether it will be made widely available to all Canadians trying to manage obesity and CKD. Study volunteers are an important part of moving medical care forward.

You may qualify to participate in this study if you:

Have a body mass index (BMI) ≥27 kilogram/square meter (kg/m²).
Have either no T2D with an HbA1c <6.5%, or have T2D with an HbA1c
- 10.5%, and treated with diet and exercise only with stable doses of up to 3 oral antihyperglycemic medications, with or without basal insulin.
Are on stable treatment, for at least 90 days before screening.
Have been diagnosed with chronic kidney disease (CKD).

You may not qualify to participate if you:

Have a self-reported change in body weight >5 kilogram (kg) (11 pounds) within 90 days before screening.
Have used in 90 days before the screening any of the following: Dipeptidyl Peptidase IV (DPP4) inhibitors, amylin analogs, glucagon-like peptide-RA (GLP-RA), gastric inhibitory polypeptide (GIP)/GIP-1 RA, and short acting or rapid acting of U500 Insulins
Have a prior or planned surgical treatment for obesity
Have Type 1 Diabetes (T1D)
Have acute or chronic hepatitis
Have a history of malignant disease within 5 years before screening.

There are other eligibility requirements that the study doctor will review. Only the study doctor can finally determine whether you are eligible to participate in the study or not.

Click the JOIN button if you think you might be eligible for this study.

All information about you will be kept confidential and will never be used or disclosed for any purpose not described in our Privacy Policy.

After providing us with your contact information, a research professional will get in touch to further assess your eligibility, answer any questions you have about the study, and determine if you qualify for participation.

Click the JOIN button if you think you might be eligible for this study.

Please complete the form below with your contact information.

Terms and Conditions

All information about you will be kept confidential and will never be used or disclosed for any purpose not described in our Privacy Policy.

After providing us with your contact information, a research professional will get in touch to further assess your eligibility, answer any questions you have about the study, and determine if you qualify for participation.

Retatrutide Study for Participants With Obesity and Chronic Kidney Disease

Click the JOIN button if you think you might be eligible for this study.

All information about you will be kept confidential and will never be used or disclosed for any purpose not described in our Privacy Policy.

After providing us with your contact information, a research professional will get in touch to further assess your eligibility, answer any questions you have about the study, and determine if you qualify for participation.