Diabetes is a condition in which your blood glucose, or blood sugar, levels are too high. With type 2 diabetes, the more common type, your body does not make or use insulin well. Insulin is a hormone that helps glucose get into your cells to give them energy. Without insulin, too much glucose stays in your blood. Over time, high blood glucose can lead to serious problems with your heart, eyes, kidneys, nerves, and gums/teeth.
Do you have type 2 diabetes?
This clinical research study is looking at the safety and effectiveness of an investigational medication option for volunteers with type 2 diabetes.
Would you like to take part in type 2 diabetes research?
As a volunteer in a research study, you’ll receive study-related medical care from the study doctor and regular follow up of your diabetes to monitor the safety and effectiveness of the care you’ll receive. Study volunteers are an important part of moving medical care forward.
You may qualify to participate in this study if you:
- Are 18 years of age or older at the time of giving informed consent
- Have been diagnosed with type 2 diabetes mellitus 180 days or more before screening
- Have not been treated with insulin. The following exceptions are permitted: short term insulin treatment for a maximum of 14 days before screening and/or prior insulin treatment for gestational diabetes
- Have been treated with stable doses of daily or weekly GLP-1 receptor agonist according to local label for the treatment of diabetes for 90 days or more before screening. DPP 4 inhibitors must be discontinued at randomization
- Body mass index (BMI) below or equal to 40.0 kg/m^2
You may not qualify to participate in this study if you:
- Are a female who is pregnant, breast feeding or intends to become pregnant or is of childbearing potential and not using a highly effective contraceptive method
- Anticipate an initiation or change in concomitant medication known to affect weight or glucose metabolism
- Treatment with any medication for the indication of diabetes or obesity other than stated in the inclusion criteria within 90 days before screening
- Any episodes of diabetic ketoacidosis within 90 days before screening
- Have a presence or history of pancreatitis within 180 days before screening
- Have any of the following: myocardial infarction, stroke, hospitalization for unstable angina pectoris or transient ischemic attack within 180 days before screening
- Have chronic heart failure classified as being in the New York Heart Association Class IV at screening
- Have uncontrolled and potentially unstable diabetic retinopathy or maculopathy
There are other eligibility requirements that the study doctor will review. Only the study doctor can determine whether you are eligible to participate in the study or not.
Fill out our diabetes questionnaire for priority access to all our diabetes studies: https://joinastudy.ca/questionnaire/diabetes/