Are you struggling with being overweight, and also have type 2 diabetes?
The purpose of this study is to find out whether an experimental medication helps people living with obesity and type 2 diabetes to lose weight.
Would you like to take part?
As a volunteer in a research study, you’ll receive study-related medical care from the study doctor and regular follow-up of your health to monitor the effectiveness of the care you’ll receive. The results of this research will be used to find out if the investigational medication being studied will be of benefit to others struggling with obesity and weight loss, and whether it will be made widely available to all Canadians trying to manage obesity. Study volunteers are an important part of moving medical care forward.
You may qualify to participate in this study if you:
- Are female or male, 18 years of age or older at the time of signing informed consent
- Have a history of at least one self-reported unsuccessful dietary effort to lose body weight
- Have a body mass index (BMI) greater than or equal to 27 kg/m^2
- Have been diagnosed with type 2 diabetes > 180 days before screening
- Are currently being treated with either lifestyle intervention or:
- Stable treatment for at least 90 days before screening with 1-3 marketed oral antidiabetic drugs as a single agent or in combination, according to local practice
- For up to 30% of participants the following concomitant medication is allowed:
- Treatment for any indication with a stable dose of glucagon-like peptide-1 (GLP-1) containing medication, stable for at least 1 year before screening
- Treatment with basal insulin minimum stable for at least 90 days before screening
You may not qualify to participate if you:
- Have been treated with any type of insulin within 90 days before screening apart from those randomized under the above criteria
- Have been treated or intent to treat with any medication prescribed for the indication of weight management within 180 days before screening
- Have had any clinically significant or severe hypoglycemic episodes with 180 days before screening
- Have uncontrolled and potentially unstable diabetic retinopathy or maculopathy
- Have uncontrolled thyroid disease
There are other eligibility requirements that the study doctor will review. Only the study doctor can finally determine whether you are eligible to participate in the study or not.
