{"id":35782,"date":"2026-04-09T10:36:26","date_gmt":"2026-04-09T14:36:26","guid":{"rendered":"https:\/\/joinastudy.ca\/?p=35782"},"modified":"2026-04-09T10:36:26","modified_gmt":"2026-04-09T14:36:26","slug":"longevity-genes-epigenetics-biological-clocks","status":"publish","type":"post","link":"https:\/\/joinastudy.ca\/fr\/longevity-genes-epigenetics-biological-clocks\/","title":{"rendered":"Longevity Genes, Epigenetics &#038; Biological Clocks"},"content":{"rendered":"<p><span data-contrast=\"auto\">Welcome back to\u00a0JoinAStudy\u2019s\u00a0ongoing series on Longevity and Aging! In the first article of this series, we explored the biological processes that cause aging. Scientists now know aging is not controlled by a single factor but by many cellular systems that gradually lose efficiency over time.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">The next big question researchers are trying to answer is equally important:\u00a0<\/span><b><span data-contrast=\"auto\">how do we measure aging?<\/span><\/b><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Two people of the same chronological age can have\u00a0very different\u00a0levels of health and disease risk. Modern longevity science is focused on\u00a0identifying\u00a0biological markers that reveal how quickly the body is\u00a0actually aging\u00a0at the cellular level. Much of this research centers on three closely related areas:\u00a0<\/span><b><span data-contrast=\"auto\">genetics, epigenetics, and biological aging clocks.<\/span><\/b><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<h4 aria-level=\"4\"><i><span data-contrast=\"none\">Are Longevity Genes Real?<\/span><\/i><span data-ccp-props=\"{&quot;134245418&quot;:true,&quot;134245529&quot;:true,&quot;335559738&quot;:80,&quot;335559739&quot;:40}\">\u00a0<\/span><\/h4>\n<p><span data-contrast=\"auto\">Certain genetic markers do appear to influence the\u00a0maximum\u00a0lifespan of a person, which obviously varies\u00a0greatly depending\u00a0on the individual.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Researchers studying exceptionally long-lived populations, including centenarians, have\u00a0identified\u00a0genetic variants that may contribute to longevity. For example, variants of the\u00a0<\/span><b><span data-contrast=\"auto\">FOXO3<\/span><\/b><span data-contrast=\"auto\">\u00a0gene are commonly found in people who live past 100 years. These genes are involved in processes like cellular repair, stress resistance, and metabolism.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">But genetics alone do not\u00a0determine\u00a0lifespan.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Studies of twins suggest inherited genes account for only about\u00a0<\/span><b><span data-contrast=\"auto\">20\u201330% of lifespan differences<\/span><\/b><span data-contrast=\"auto\">. The remaining variation is\u00a0largely influenced\u00a0by lifestyle factors such as diet, physical activity, sleep, and exposure to environmental stressors.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Research supported by the\u00a0<\/span><i><span data-contrast=\"auto\">National Institute on Aging<\/span><\/i><span data-contrast=\"auto\">\u00a0emphasizes that while genes set the baseline for health, daily behaviors play a far greater role in shaping how quickly we age.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<h4 aria-level=\"4\"><i><span data-contrast=\"none\">Epigenetics: How Lifestyle Influences Your Genes<\/span><\/i><span data-ccp-props=\"{&quot;134245418&quot;:true,&quot;134245529&quot;:true,&quot;335559738&quot;:80,&quot;335559739&quot;:40}\">\u00a0<\/span><\/h4>\n<p><span data-contrast=\"auto\">A major discovery in aging research over the past two decades is the field of\u00a0<\/span><b><span data-contrast=\"auto\">epigenetics<\/span><\/b><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Epigenetics refers to chemical modifications that control whether genes are turned\u00a0<\/span><b><span data-contrast=\"auto\">on or off<\/span><\/b><span data-contrast=\"auto\">. These changes do not alter the DNA sequence itself, but they influence how cells interpret genetic instructions.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Factors known to affect epigenetic activity include:<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<ul>\n<li aria-setsize=\"-1\" data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"11\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Diet and nutrition<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li aria-setsize=\"-1\" data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"11\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">Exercise habits<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li aria-setsize=\"-1\" data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"11\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" data-aria-posinset=\"3\" data-aria-level=\"1\"><span data-contrast=\"auto\">Stress levels<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li aria-setsize=\"-1\" data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"11\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" data-aria-posinset=\"4\" data-aria-level=\"1\"><span data-contrast=\"auto\">Sleep quality<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li aria-setsize=\"-1\" data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"11\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" data-aria-posinset=\"5\" data-aria-level=\"1\"><span data-contrast=\"auto\">Exposure to toxins or pollution<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><span data-contrast=\"auto\">Scientists have found that these influences can alter gene expression patterns linked to inflammation, metabolism, and cellular repair.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Researchers at\u00a0<\/span><a href=\"https:\/\/hms.harvard.edu\/news\/epigenetics-explained\"><span data-contrast=\"none\">Harvard Medical School<\/span><\/a><span data-contrast=\"auto\">\u00a0describe epigenetics as one of the main ways lifestyle factors translate into long-term biological changes. In some cases, these modifications may even be reversible, which is why preventive medicine has become central to longevity research.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<h4 aria-level=\"4\"><i><span data-contrast=\"none\">Biological Clocks: Measuring the Aging Process<\/span><\/i><span data-ccp-props=\"{&quot;134245418&quot;:true,&quot;134245529&quot;:true,&quot;335559738&quot;:80,&quot;335559739&quot;:40}\">\u00a0<\/span><\/h4>\n<p><span data-contrast=\"auto\">Because aging is complex, scientists need ways to measure it more accurately than simply counting years. One of the most promising tools developed in the past decade is the\u00a0<\/span><b><span data-contrast=\"auto\">epigenetic clock<\/span><\/b><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">These clocks analyze chemical markers on DNA called\u00a0<\/span><b><span data-contrast=\"auto\">methylation patterns<\/span><\/b><span data-contrast=\"auto\">, which change predictably as people age. By measuring these patterns, researchers can estimate a person\u2019s\u00a0<\/span><b><span data-contrast=\"auto\">biological age<\/span><\/b><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">One of the most widely used models is the\u00a0<\/span><b><span data-contrast=\"auto\">Horvath Clock<\/span><\/b><span data-contrast=\"auto\">, developed by geneticist Steve Horvath. This method analyzes DNA samples from blood or other tissues to estimate biological aging across multiple organ systems.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Biological age measurements are increasingly used in research studies to evaluate whether interventions (such as diet changes, medications, or lifestyle programs)\u00a0appear to slow\u00a0the aging process.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">According to research published in\u00a0<\/span><a href=\"https:\/\/www.nature.com\/articles\/s43587-021-00080-0\"><i><span data-contrast=\"none\">Nature<\/span><\/i><\/a><span data-contrast=\"auto\">, epigenetic clocks have become one of the most powerful tools for studying aging at the molecular level.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<h4 aria-level=\"4\"><i><span data-contrast=\"none\">Telomeres: The First Biological Aging Marker<\/span><\/i><span data-ccp-props=\"{&quot;134245418&quot;:true,&quot;134245529&quot;:true,&quot;335559738&quot;:80,&quot;335559739&quot;:40}\">\u00a0<\/span><\/h4>\n<p><span data-contrast=\"auto\">Before epigenetic clocks were developed, scientists focused heavily on\u00a0<\/span><b><span data-contrast=\"auto\">telomeres<\/span><\/b><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Telomeres are protective caps at the ends of chromosomes that help preserve DNA during cell division. Each time a cell divides, these caps become slightly shorter. When they become too short, the cell can no longer divide and may enter a damaged state.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Shorter telomeres have been associated with aging-related diseases, including cardiovascular disease and certain cancers.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">However, while telomere length is still studied, many researchers now believe it is only\u00a0<\/span><b><span data-contrast=\"auto\">one piece of a much larger puzzle<\/span><\/b><span data-contrast=\"auto\">. Epigenetic measurements\u00a0appear to provide\u00a0a more comprehensive picture of aging across the body.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Organizations such as the\u00a0<\/span><a href=\"https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/ageing-and-health\"><span data-contrast=\"none\">World Health Organization<\/span><\/a><span data-contrast=\"auto\">\u00a0highlight the growing importance of molecular biomarkers for understanding population health and age-related disease risk.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<h4 aria-level=\"4\"><i><span data-contrast=\"none\">Can Biological Age Be Slowed?<\/span><\/i><span data-ccp-props=\"{&quot;134245418&quot;:true,&quot;134245529&quot;:true,&quot;335559738&quot;:80,&quot;335559739&quot;:40}\">\u00a0<\/span><\/h4>\n<p><span data-contrast=\"auto\">An important implication of epigenetic research is that biological aging may be more flexible than previously believed.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Early studies suggest certain behaviors may slow biological aging markers, including:<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<ul>\n<li aria-setsize=\"-1\" data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"12\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Regular physical activity<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li aria-setsize=\"-1\" data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"12\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">Maintaining a healthy weight<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li aria-setsize=\"-1\" data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"12\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" data-aria-posinset=\"3\" data-aria-level=\"1\"><span data-contrast=\"auto\">Consistent sleep patterns<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li aria-setsize=\"-1\" data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"12\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" data-aria-posinset=\"4\" data-aria-level=\"1\"><span data-contrast=\"auto\">Balanced diets rich in plant-based nutrients<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li aria-setsize=\"-1\" data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"12\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" data-aria-posinset=\"5\" data-aria-level=\"1\"><span data-contrast=\"auto\">Avoiding smoking and excessive alcohol<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><span data-contrast=\"auto\">While scientists are still studying how large these effects can be, the evidence increasingly supports the idea that\u00a0<\/span><b><span data-contrast=\"auto\">aging is not purely predetermined<\/span><\/b><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Instead, the pace of aging appears to depend on the balance between biological damage and the body\u2019s ability to repair it.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<h4 aria-level=\"4\"><i><span data-contrast=\"none\">The Next Frontier in Longevity Research<\/span><\/i><span data-ccp-props=\"{&quot;134245418&quot;:true,&quot;134245529&quot;:true,&quot;335559738&quot;:80,&quot;335559739&quot;:40}\">\u00a0<\/span><\/h4>\n<p><span data-contrast=\"auto\">Understanding genes and biological clocks helps researchers answer a critical question:\u00a0<\/span><b><span data-contrast=\"auto\">why do some people\u00a0age\u00a0faster than others?<\/span><\/b><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">But another major area of longevity science focuses on metabolism \u2014 the chemical processes that allow cells to produce energy and\u00a0maintain\u00a0themselves.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Scientists are now investigating how metabolic pathways influence aging and whether certain dietary strategies or medications can improve these processes.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">In the next article in this series,\u00a0we\u2019ll\u00a0explore how\u00a0<\/span><b><span data-contrast=\"auto\">metabolism, fasting, and cellular repair systems<\/span><\/b><span data-contrast=\"auto\">\u00a0are becoming central to modern longevity research.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p aria-level=\"1\"><b><span data-contrast=\"none\">Sources<\/span><\/b><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;134245418&quot;:true,&quot;134245529&quot;:true,&quot;335559738&quot;:322,&quot;335559739&quot;:322}\">\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/www.nia.nih.gov\/health\/genes-longevity-and-aging\"><span data-contrast=\"none\">https:\/\/www.nia.nih.gov\/health\/genes-longevity-and-aging<\/span><\/a><br \/>\n<a href=\"https:\/\/hms.harvard.edu\/news\/epigenetics-explained\"><span data-contrast=\"none\">https:\/\/hms.harvard.edu\/news\/epigenetics-explained<\/span><\/a><br \/>\n<a href=\"https:\/\/www.nature.com\/articles\/s43587-021-00080-0\"><span data-contrast=\"none\">https:\/\/www.nature.com\/articles\/s43587-021-00080-0<\/span><\/a><br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4015143\/\"><span data-contrast=\"none\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4015143\/<\/span><\/a><br \/>\n<a href=\"https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/ageing-and-health\"><span data-contrast=\"none\">https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/ageing-and-health<\/span><\/a><br \/>\n<a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.aar3191\"><span data-contrast=\"none\">https:\/\/www.science.org\/doi\/10.1126\/science.aar3191<\/span><\/a><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Welcome back to\u00a0JoinAStudy\u2019s\u00a0ongoing series on Longevity and Aging! In the first article of this series, we explored the biological processes that cause aging. Scientists now know aging is not controlled by a single factor but by many cellular systems that gradually lose efficiency over time.\u00a0 The next big question researchers are trying to answer is<\/p>\n","protected":false},"author":964,"featured_media":16735,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[513,515],"tags":[],"class_list":["post-35782","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-and-wellness","category-health-guides","category-513","category-515","description-off"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.2 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Longevity Genes, Epigenetics &amp; Biological Clocks - JoinAStudy.ca<\/title>\n<meta name=\"description\" content=\"Certain genetic markers do appear to influence the\u00a0maximum\u00a0lifespan of a person, which obviously varies\u00a0greatly depending\u00a0on the individual.\u00a0\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/joinastudy.ca\/fr\/longevity-genes-epigenetics-biological-clocks\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Longevity Genes, Epigenetics &amp; 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