The availability of COVID-19 vaccines for young children in the U.S. could shrink this fall as the Food and Drug Administration (FDA) considers ending the emergency use authorization (EUA) for Pfizer-BioNTech’s vaccine in kids ages 6 months to 4 years. Pfizer says it is in discussions with the FDA and has asked to keep the
A recent clinical trial is offering new hope in the fight against HIV. Researchers tested a new type of vaccine using mRNA technology—the same method used in COVID-19 vaccines—to see if it could trigger strong immune responses against the virus. The trial, called HVTN 302, tested three different versions of an HIV vaccine in 108
The FDA has approved a safer dosing schedule for Eli Lilly’s Alzheimer’s drug, Kisunla, which could make it more appealing to doctors and patients. The updated schedule reduces the risk of a serious side effect called ARIA-E—brain swelling caused by anti-amyloid drugs. Originally, Kisunla was given in higher doses early on. Now, the drug will
The U.S. Food and Drug Administration (FDA) has approved Nucala (mepolizumab) as an add-on treatment for adults with chronic obstructive pulmonary disease (COPD) who continue to have flare-ups despite using triple inhaled therapy. Nucala is the first biologic drug specifically approved for COPD patients with an “eosinophilic phenotype”—a group defined by having high levels of
Welcome to our series of blogs honoring Clinical Trials Day 2025, recognized on May 20th! Clinical trials are essential studies conducted to evaluate the safety, efficacy, and effectiveness of medical interventions, including drugs, treatments, devices, and diagnostic procedures. These trials follow a structured and rigorous process to generate reliable evidence for medical advancements, and to
AstraZeneca is making big moves with its inhaler, Breztri Aerosphere, aiming to expand its use beyond chronic obstructive pulmonary disease (COPD) to also treat asthma. This could bring the company closer to its sales goal of $3 to $5 billion a year. Breztri is a 3-in-1 inhaler that combines three drugs to help people breathe
A recent international study has found that a single dose of a new RSV vaccine, called RSVPreF3 OA, can protect adults aged 60 and older from serious lung infections caused by the respiratory syncytial virus (RSV) for up to three seasons. The study involved over 24,000 older adults across 17 countries and tested how well
The FDA has approved Novo Nordisk’s drug Ozempic for a new use: reducing the risk of kidney disease worsening, kidney failure, and death from cardiovascular disease in adults with Type 2 diabetes and chronic kidney disease (CKD). This approval is significant because Ozempic is now the first drug in its class (GLP-1 receptor agonists) with
Novo Nordisk is exploring a higher-dose version of semaglutide to enhance weight loss treatments. In a recent phase 3b clinical trial called STEP UP, a 7.2-mg weekly dose of semaglutide helped participants lose an average of 20.7% of their body weight over 72 weeks. This significantly outperformed the 2.4-mg dose marketed as Wegovy, which led
Arrowhead Pharmaceuticals announced positive results from its Phase 3 PALISADE study on plozasiran, a new drug for treating familial chylomicronemia syndrome (FCS). FCS is a rare genetic condition that causes extremely high triglyceride levels, leading to serious health issues like acute pancreatitis. Currently, there are no approved treatments for FCS in the United States or
