Recruiting now

Study for Adult Participants With Uncontrolled Moderate to Severe Asthma

Enrolling at: Windsor
Phase 2Study phase
18–75Age range
1 siteResearch locations

About this study

Do you suffer from uncontrolled, moderate to severe asthma?

The purpose of this study is to assess the safety and efficacy of brenipatide at different dose levels compared with placebo in participants with moderate-to-severe asthma.

Study participation will last approximately 65 weeks, including screening, treatment, and follow-up periods.

Would you like to take part?

As a volunteer in a research study, you’ll receive study-related medical care from the study doctor and regular follow up of your condition to monitor the safety and effectiveness of the care you’ll receive. Study volunteers are an important part of moving medical care forward.

Who may qualify

You may qualify if
  • Have physician-diagnosed asthma and have received a physician-prescribed asthma controller medication for at least 12 months prior to screening visit.
  • Have an asthma control questionnaire-6 (ACQ-6) score of ≥1.5 on 2 out of 3 visits before randomization.
  • Have a history of 1 severe asthma exacerbation that led to systemic glucocorticoid treatment in the last 12 months prior to screening visit.
This study may not be a fit if
  • Have an established diagnosis of occupational asthma
  • Have any known pre-existing, clinically important lung condition other than asthma, including but not limited to:
    • chronic respiratory infection
    • bronchiectasis
    • pulmonary fibrosis
    • allergic bronchopulmonary aspergillosis
    • emphysema
    • chronic bronchitis
    • eosinophilic granulomatosis with polyangiitis
    • chronic obstructive pulmonary disease, and
    • other mimics of asthma, that is, vocal cord dysfunction.
  • Have a current or recent acute, active infection, for at least 30 days before screening visit and up to the randomization visit.
Every study has additional criteria the research site will review with you.

What participation may involve

  • Regular visits with the study team at no cost
  • Study assessments and health monitoring throughout
  • Check-ins between visits
  • Informed consent before anything begins — questions welcome

What participants may receive

  • Study-related care from a physician-led team
  • Study assessments at no cost
  • Reimbursement for reasonable travel, where applicable
Specifics vary by study and site, and are never a guarantee of benefit. Being in a study is not a substitute for regular medical care.
Participating research sites

Where this study is enrolling

WINDSOR, ONWindsor Health CentrePrincipal investigator: Dr. Syed Anees, Dr. Sabeen AnwarView site →

Learn more

About the condition

Asthma

Asthma is a long-term condition of the airways, the tubes that carry air in and out of your lungs. In asthma those tubes can swell, tighten and fill…

Read about this condition →
About the condition

Chronic Obstructive Pulmonary Disease (COPD)

Chronic obstructive pulmonary disease, or COPD, is a long-term lung condition in which the airways are narrowed and the small air sacs deep in the lungs are damaged.…

Read about this condition →
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Common questions

Do I have to decide now?
No. Answering the questions is not a commitment — it simply lets the research team see whether this study may be appropriate and contact you to talk it through.
Will it cost me anything?
No. Study visits and study assessments are provided at no cost, and reasonable travel may be reimbursed where applicable.
What happens after I submit the form?
A member of the research team reviews your answers and contacts you — usually within two business days — to answer questions and review the next steps.
Could I receive a placebo?
Some studies compare a treatment with a placebo. Whether this study does is explained clearly during informed consent, before you decide anything.
Can I leave the study after it starts?
Yes. Participation is always voluntary. You can withdraw at any time without giving a reason and without it affecting your regular medical care.
Request contact

Ask the research site to contact you

Your answers go to our research team and the study site, help the team prepare before they call — and completing the form doesn’t obligate you to take part.
Study interest form

See if you may qualify

A few quick questions — about a minute. Your answers help the research team prepare before they contact you.

For anyone under 18, a parent or legal guardian should complete this form and would need to consent on their behalf.

See if you may qualify →