RecruitingAsthma
Asthma is a long-term condition of the airways, the tubes that carry air in and out of your lungs. In asthma those tubes can swell, tighten and fill with mucus, so moving air takes more effort. Symptoms come and go, and they often flare after contact with a trigger such as a cold virus, cold air, exercise, smoke or an allergen.
- Diagnosed asthma in Canada rose 67% over 12 years, from 2.1 million people (6.5%) in 2000-2001 to 3.8 million people (10.8%) in 2011-2012. Source: Public Health Agency of Canada, Canadian Chronic Disease Surveillance System, 2011-2012
- Diagnosed asthma varied widely across the country in 2011-2012, from 3.8% in Nunavut to 12.1% in Ontario. Source: Public Health Agency of Canada, Canadian Chronic Disease Surveillance System, 2011-2012
- Asthma was reported for 6.4% of children and youth aged 1 to 17 living in the provinces in 2023. Source: Public Health Agency of Canada, Canadian Health Survey on Children and Youth, 2023
What asthma is, and what it is not
Asthma is often described as a childhood condition that people grow out of. It does often start in childhood, but it can begin at any age, including after 50. Adult-onset asthma is sometimes linked to workplace exposures, a chest infection, or allergies that develop later in life, and it is identified with the same breathing tests used in younger people.
Asthma is also not the same as COPD, although both narrow the airways and cause breathlessness. Asthma tends to vary from day to day and often improves a good deal after an inhaled bronchodilator, while the airflow limitation in COPD does not fully reverse. Some people have features of both. Because asthma varies, one normal breathing test does not always settle the question, which is why a clinician may repeat testing or add a challenge test.
Signs and symptoms
- Wheezing, a whistling sound when you breathe out
- Coughing, often worse at night or early in the morning
- Shortness of breath, or feeling that you cannot get a full breath
- Tightness or pressure in the chest
- Waking at night because of coughing or breathing trouble
- Getting more out of breath than usual during everyday activity
- Needing a reliever inhaler more often than usual
Symptoms differ from person to person and change over time. Many people have long stretches with very little trouble, then a flare set off by a virus, cold air, exercise, smoke or an allergen.

What raises the risk
Some things cannot be changed:
- A family history of asthma, eczema or hay fever
- Being born early or with a low birth weight
- Sex and age, with asthma more common in boys during childhood and in women during adulthood
Others can often be worked on, usually with support from a health care team:
- Tobacco smoke, including second-hand smoke and vaping aerosol
- Indoor allergens such as dust mites, mould, cockroaches and animal dander
- Outdoor air pollution, traffic exhaust and wildfire smoke
- Workplace exposures such as flour dust, isocyanates, wood dust and cleaning chemicals
- Carrying extra weight, which is linked with harder-to-control asthma
How asthma is diagnosed in Canada
Asthma is usually confirmed with spirometry, a breathing test that measures how much air you can blow out and how fast, before and after an inhaled bronchodilator medicine. If spirometry is normal but asthma is still suspected, a methacholine challenge test or an exercise challenge test may be used to see whether the airways narrow. A clinician may also look at peak flow readings kept over time, arrange allergy testing by skin prick or blood IgE, and in some centres use a FeNO breath test that measures airway inflammation.
Treatment and day-to-day management
Clinical research for Asthma is enrolling. See the current studies
Asthma care in Canada aims to settle inflammation in the airways, keep symptoms from limiting your day, and lower the chance of a flare-up. Depending on how often you have symptoms and what sets them off, a health care team may discuss:
- Inhaled medicines taken by puffer, spacer or nebuliser, including short-acting relievers and longer-acting controller inhalers that contain corticosteroids
- Oral medicines, including corticosteroid tablets during a flare-up and leukotriene receptor antagonists
- Biologic injectable therapies, handled through specialist severe asthma clinics for a small group of people whose symptoms continue on inhaled treatment
- Asthma education and a written asthma action plan, from certified respiratory educators, pharmacists and family practices
- Trigger assessment, allergy testing and allergen immunotherapy through allergists and respirologists
Inhaler technique, timing and choice all matter, and what suits one person will not suit another. These are decisions for you and your own clinician, and this page is not a recommendation about any of them.
When to talk to a doctor
- Call 911 if you are struggling to breathe, cannot speak in full sentences, your lips or fingernails look blue or grey, or your reliever inhaler is not helping.
- Seek urgent medical care the same day if you need your reliever inhaler more often than every four hours, or if symptoms keep waking you at night.
- Book a review with your family doctor, nurse practitioner or pharmacist if you use a reliever inhaler more than twice a week, or if asthma is limiting your usual activities.
Why clinical research matters for asthma
A large share of people living with asthma in Canada still have symptoms despite treatment. Asthma Canada reported that only 45 percent of respondents to its 2024 national survey believed their asthma was well controlled. Researchers still do not fully understand why some people respond to standard inhalers while others do not, or how to pick out the different biological subtypes of asthma early. Studies running in Canada include new and existing biologic therapies for severe or eosinophilic asthma, single-inhaler anti-inflammatory reliever strategies, digital and connected inhaler tools that track how medicines are actually used, and research on air quality and wildfire smoke exposure.
Clinical studies are how those questions get answered. Taking part is voluntary, you give informed consent before anything begins, and you can stop at any time without affecting the care you get from your own doctor. Joining a study does not mean giving up your current treatment, and no one can say in advance whether a study will help you personally.
Learn more from Canadian sources
- Asthma Canada
- Canadian Lung Association: Lung Health Information Line
- Public Health Agency of Canada: asthma and COPD in Canada
- Public Health Agency of Canada: chronic conditions in childhood
Where this information comes from (4 sources)
- Asthma Canada, A Snapshot of Asthma in Canada (National Asthma Survey), 2024
- Public Health Agency of Canada, Asthma and Chronic Obstructive Pulmonary Disease (COPD) in Canada, 2018
- Public Health Agency of Canada, Prevalence of chronic conditions in childhood, 2023
- World Health Organization, Asthma fact sheet, 2026
This page is written in plain language for people considering clinical research. It is general health information, not medical advice, and it does not replace a conversation with your own doctor or nurse practitioner.
Common questions
Can asthma start later in life?
Yes. Although asthma is often diagnosed in childhood, it can also begin in adulthood, including after age 50. Adult-onset asthma is sometimes linked to workplace exposures, respiratory infections or allergies that develop later, and it is diagnosed with the same breathing tests used in younger people.
How is asthma different from COPD?
Both conditions narrow the airways and cause breathlessness, but asthma tends to vary from day to day and often improves a good deal after an inhaled bronchodilator. COPD is usually linked to long-term exposure such as smoking and involves airflow limitation that does not fully reverse. Some people have features of both, and spirometry helps a clinician tell them apart.
Why might someone with asthma be invited to a clinical trial?
Trials look at questions current care has not answered, such as how to help people whose symptoms continue despite inhaled treatment. Taking part usually involves extra breathing tests and monitoring visits, and it is voluntary at every stage. A research team explains the study in detail during informed consent, and you can withdraw at any time.
- Talk to your doctor. This guide is information, not medical advice.
- See the current studies. 6 studies for Asthma
- Not ready yet? Join the community and hear when a study may match the health areas you care about.
Studies for Asthma
See all Asthma trials →
Recruiting
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Study for Patients With Idiopathic Pulmonary Fibrosis (IPF)
Windsor, Ontario
RecruitingChronic Obstructive Pulmonary Disease (COPD) · Respiratory
Study in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
Windsor, Ontario
RecruitingChronic Obstructive Pulmonary Disease (COPD) · Respiratory
Study of Initiating DepemokImab Early Therapy in Chronic Obstructive Pulmonary Disorder (COPD)
Windsor, Ontario
RecruitingChronic Obstructive Pulmonary Disease (COPD) · Respiratory
Study of Lunsekimig Compared With Placebo in Adult Participants With COPD
Windsor, Ontario
RecruitingChronic Obstructive Pulmonary Disease (COPD) · Respiratory
Study of Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation
Windsor, Ontario


