Do you have elevated lipoprotein levels and suffer from cardiovascular disease?
Would you like to take part? Would you like a friend or family member to take part?
As a volunteer in a research study, you will receive personal study-related medical care from the study doctor and regular follow up on your health to monitor the effectiveness of the care you will receive. The results of this research will be used to find out if the experimental medication being studied will be of benefit to others with elevated lipoprotein levels and cardiovascular disease or not. Study volunteers are an important part of moving medical care forward.
You may qualify to participate in this study if you:
- Have Lp(a) ≥175 nanomoles per liter (nmol/L)
- Meet one of the following criteria:
- Have had a prior atherosclerotic cardiovascular disease (ASCVD) event (such as heart attack, stroke, or procedure to restore blood flow to the heart or other parts of the body) within 10 years prior to screening
- Are at risk for a first ASCVD event, defined as one or more of the following:
- Documented coronary artery disease (CAD), carotid stenosis, or peripheral artery disease (PAD) without a history of ASCVD event
- A high coronary artery calcium (CAC) score
- Reduced kidney function with diabetes
- Combination(s) of high risk factors
You may not qualify to participate in this study if you:
- Have experienced a major cardiovascular event or surgery, such as heart attack, stroke, or procedure to restore blood flow to the heart or other parts of the body, within 90 days prior to screening or occurring between screening and randomization
- Are planning or expected to undergo a procedure to restore blood flow in the arteries or a major heart surgery during the study
- Have uncontrolled high blood pressure
- Have New York Heart Association (NYHA) class III or IV heart failure
- Have undergone a procedure to remove cholesterol from the blood within 90 days of screening, or have a planned procedure during the study
- Have severe kidney impairment
- Have had cancer within 5 years prior to screening
There are other eligibility requirements that the study doctor will review. Only the study doctor can finally determine whether you are eligible to participate in the study or not.
Participants who qualify for this study will receive a study-related health examination at no cost, as well as possible compensation for time and travel.
