Roche AG has reported strong results from a mid-stage clinical trial of its experimental weight loss drug, CT-388, showing that study subjects lost an average of 22.5% of their body weight after 48 weeks of observation. Based on these findings, the company plans to move the drug into large Phase 3 trials later this year.
Autoimmune diseases occur when the immune system (normally responsible for fighting infections) mistakenly attacks the body’s own tissues. This misdirected response can cause inflammation, pain, fatigue, and damage to organs or entire systems. More than 80 autoimmune conditions have been identified by medical professionals, but some are far more common and better understood than others.
Les maladies auto-immunes surviennent lorsque le système immunitaire (normalement chargé de lutter contre les infections) attaque par erreur les propres tissus de l’organisme. Cette réponse inappropriée peut provoquer une inflammation, des douleurs, de la fatigue ainsi que des dommages touchant des organes ou des systèmes entiers. Plus de 80 maladies auto-immunes ont été
Bienvenue dans la partie 2 de notre série en cours consacrée aux maladies auto-immunes. Aujourd’hui, nous allons nous pencher sur les maladies auto-immunes qui touchent spécifiquement le système endocrinien et provoquent des déséquilibres hormonaux pouvant perturber les fonctions naturelles de l’organisme. Les maladies auto-immunes surviennent lorsque le système immunitaire (normalement chargé de lutter contre les
Bienvenue dans la première partie d’une série en plusieurs volets consacrée à la classification relativement peu étudiée des maladies auto-immunes. Au cours des prochaines semaines, nous explorerons les différents types de ces maladies chroniques et la façon dont les normes de soins évoluent à mesure que de nouvelles recherches et options thérapeutiques deviennent disponibles. De
A small but groundbreaking new study hints that gene editing may one day offer a permanent fix for dangerously high cholesterol. Published in the New England Journal of Medicine, the pilot trial tested a CRISPR-Cas9–based treatment in 15 people with severe cholesterol problems. CRISPR works like tiny biological scissors, cutting and switching off specific genes.
Eli Lilly has reported impressive results from a large Phase 3 clinical trial of its experimental obesity drug, retatrutide. The drug helped patients lose significantly more weight than expected and also reduced knee pain linked to osteoarthritis. However, some patients stopped treatment due to side effects, raising questions about how well people can tolerate the
A new clinical trial has some exciting news for people with type 2 diabetes: a daily pill utilizing the molecule orforglipron helped participants lose almost as much weight as popular injectable drugs like Ozempic. And because it’s taken orally, it could make treatment much simpler and more accessible. The study followed more than 1,600 adults across 10
Curious about the science behind today’s most talked-about diabetes and weight-management treatments? Our new, four-part blog series on GLP-1 Agonists will break down everything you need to know — from how these drugs work, to their real-world results, side effects, and what’s coming next in the pipeline. Today, we’re taking a look at some of
Following the success of Ozempic®, Wegovy®, and other GLP-1 receptor agonists, pharmaceutical companies are racing to develop the next wave of metabolic drugs. These new therapies build on the proven benefits of currently approved GLP-1s—lowering blood sugar, supporting weight loss, and reducing cardiovascular risk—while aiming for even greater results in weight management and metabolic health.
